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|Title: ||Correlation of serum and saliva glucose concentration in fasting specimens|
|Authors: ||Espiritu, Allan Jay C.|
|Keywords: ||correlation, saliva, serum, glucose concentration, Diabetes Mellitus|
|Issue Date: ||2014|
|Abstract: ||The main objective of this study is to determine the glucose concentrations in fasting serum and saliva samples between non-diabetics and diabetics then determine if there is a correlation in the values obtained. The study intends to demonstrate the possibility of a saliva sample as an alternative to specimens collected invasively, like serum and serve as an alternative specimen in screening and monitoring Diabetes Mellitus.
Included in the study were nine diabetic patients and ten non-diabetic patients. They were scheduled for specimen collection between 7:30 AM to 9:30 AM after 8-12 hours of fasting. Nine milliliters of venous blood was collected into red-top tubes. For the saliva sample collection, subjects were instructed to rinse their mouth before collection. Unstimulated, whole saliva was collected from both groups through the “passive drool” method. The specimens were processed immediately using the Hexokinase method for glucose level determination.
The data was treated with Pearson Correlation Coefficient test and results were interpreted using an interpretation scale of Pearson Correlation Coefficient test. The researchers observed a significant correlation between fasting serum and salivary glucose levels in the diabetic subjects. However, no significant correlation was observed between fasting serum and salivary glucose levels in the non-diabetic subjects. The researchers concluded that saliva sample cannot be an alternative specimen in glucose determination. We recommend that further studies performed on saliva should be done with other related tests.|
|Appears in Collections:||Unpublished Manuscripts|
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